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What is CBG and what is it good for? (with actual data and research)

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We have a very simple mission here at Wake + Bake:

We’re here to show the world that cannabis is healthy and to share healthy cannabis recipes.

Simple, right?

But when I tell people this, the message often gets lost because of what some people think cannabis is.

“I’ve tried using it but I don’t like how it feels.”

“I used to use it when I was younger but it made me so foggy and tired. I quit years ago because I was a burnout.”

“I don’t want to get too high to function.”

I’ve heard so many responses like this over the years, that I just quickly back up and remind people that cannabis is a plant that contains TONS of compounds that won’t blast you off too the moon or glue you to the couch. 

“There’s so much more to this plant than THC,” I usually reply.

When CBD became popular and more widely available a couple of years ago, this conversation got a lot easier.

But it quickly became a bit more complicated as soon as advances in breeding brought a whole new cannabinoid into our worlds.

Enter CBG.

As soon as I started saying things like “CBD and CBG won’t get you high but have their own uses and benefits,” I started getting that confused look again.


CBG is short for cannabigerol and you don’t need to know how to pronounce that word correctly in order to understand this amazing compound.

CBG – sometimes considered a “minor cannabinoid” – used to be called “Rolls Royce of Cannabinoids” because it was difficult to find and very expensive.

But last year, a friend gifted me my first 1/2 lb of 12% CBG plant material for my birthday in October.

Since then, I’ve been able to order it online from Sacred Smoke just like CBD to make my own infusions and edibles.

I’m starting to see CBG everywhere and when I talk about it people have so many questions and stories to share.

Some readers and students have mentioned that CBG did for them what they hoped CBD or THC would in terms of mood enhancement, pain relief and anxiety reduction.

Incorporating CBG into my oils and edibles has been so helpful for me personally, that I couldn’t wait to share it with you, but I’m not just going to talk about how great I think it is or share the building mountain of anecdotal evidence in this post.

We had to go straight to the source and dive into the research that exists so we can gain a better understanding of it.

In this post, I’m going to break down everything we know about CBG that is practical that can help guide us, and nothing else.

Get ready to geek. out.

What is CBG and what's it good for?

Benefits of CBG: What is CBG good for?

Like CBD, when I see lists touting the benefits of CBG without any resources, my bullshit meter goes off the charts.

Some “resources” look more like snake oil cures than actual information.

But don’t let that scare you away from this compound.

Like CBD, CBG has been shown to be beneficial for a lot of different, and seemingly unrelated issues because of the way it interacts with the endocannabinoid system.

Here are things that we found promising research on when it comes to CBG.

CBG for Brain Health and Depression

Like other cannabinoids, in some small animal studies, CBG has shown some promise for promoting or protecting brain health.

In one study, CBG was shown to protect brain cells against damage, degeneration or impairment when used on mice with Huntington’s disease giving a shred of evidence that it could be a possible treatment for people with Huntington’s in the future.

Research has also shown that combining CBG and CBD decreased inflammation in the brain, which may make it potentially make it effective for things like ALS.

At any rate, even people without ALS or Huntington’s disease could potentially benefit from a little brain boosting supplement like CBG.

Brain inflammation may be a contributing factor to chronic depression and CBG reduces inflammation in the brain (and the rest of the body), so it may prove to be useful for depression in the future as well.

CBG has also been shown to be a more effective GABA uptake inhibitor than THC or CBD.

Low levels of GABA can contribute to anxiety and mood disorders.

While it’s unknown how much of an impact CBG has directly on GABA, it could be why many people attribute CBG to improved moods.

While all we currently have on CBG and depression is anecdotal, myself and many others have noted that regular doses of CBG seem to have a positive impact on mood and outlook.

Take that “this is your brain on drugs” commercial.

CBG for Pain

The connection between CBG and pain relief just got a brief mention in this article.

Furthermore, CBG has more potent analgesic activity […] than THC”

Like all the things on this list, we need more research to know if there’s a link between CBG and pain reduction for sure, but we had to dig a little deeper to see why CBG may be better for pain than THC.

As we discuss below and above, CBG’s anti-inflammitory response may be a big factor in pain reduction since inflammation is a contributing factor to pain, even in hard to treat neuropathic pain.

While the jury and the research is still out, CBG used alongside other treatments and cannabinoids may eventually prove to be an effective pain reliever for aches and hard to treat chronic pain.


Inflammation doesn’t just impact the brain or the neuromuscular system. It also can have a huge impact on the digestive system.

Evidence from a small study on mice showed reduced inflammation in those with inflammatory bowel disease, which impacts millions of people worldwide and currently has no cure.

Other cannabinoids have been shown to improve the ratio of good to harmful gut bacteria, reduce gut impermeability and could potentially contribute to weight loss.

This CBG mice study is just a small piece on the tiny pile of research that cannabis may be good for the gut and could potentially help folks with chronic digestive issues… down the road… when there’s more research… 

CBG for Cancer

The big C. This is always such a sensitive topic when you’re talking about cannabis.

If you’re trying to figure out how to navigate cannabis and cancer, and you’ve landed on this post, I highly recommend working with a cannabis coach alongside your medical team or finding a doctor who is well versed in cannabis.

Dr. Bonnie Goldstien has mentioned in the past that she’s seen the best results when people use both doctor recommended conventional cancer treatments and cannabis use together as opposed to using just one or the other.

From that perspective, and because drug interactions are a very real thing when it comes to CBD and CBG taken orally, it’s very important to communicate your cannabis use to your doctor when tackling any major health issue.

That being said, I’m not a doctor and what I learned about CBG and cancer was pretty exciting from an educator’s perspective.

A study on rats with colon cancer provided evidence that CBG can be used to help reduce the growth of cancer cells and tumors.

This may be because CBG has been shown to inhibit a little thing called the TRPM8 channel, which is part of the nervous system.

When this channel gets overly sensitive (or “upregulated” in science terms) it has been linked to the growth of many different types of cancers.

By inhibiting the TRPM8 channel CBG shows potential for stopping the progression of tumor growth, but… and say it with me now… we need more research.

CBG for Bladder Issues

It’s one thing to pee a little when you laugh at one of the super well written jokes and ancient puns you’ll find here on Wake + Bake. It’s another thing to suffer from chronic bladder issues.

CBG shows the most potential among the cannabinoids to treat bladder dysfunctions.

This may partially have something to do with how it impacts that TRPM8 channel.

That’s because TRPM8 also conducts sensory impulses.

When over-expressed, the TRPM8 can lead to many issues surrounding these pathways, one of which is notably bladder dysfunction.

Since CBG can inhibit TRPM8, reducing the excess sensory impulses, it shows some promise as a potential treatment for bladder dysfunction.

It also may be of interest for bladder issues because of that CBG-GABA increase, which – aside from making you feel better – can also contribute to a reduction in stress related muscle spasms.

CBG for Appetite

If you’re trying to avoid the munchies, CBG may not be for you.

However, it can be a tremendous help to those who are finding themselves without an appetite for various reasons ranging from chemotherapy to depression.

From the very limited mice study, it seems like you’d have to take much higher doses of CBG in order to increase appetite.

I’ve found this to be true for me as well. Unless I take a lot of CBG, I don’t notice an increase in appetite, unless I’m also taking a lot of THC which is it’s own appetite monster.

Dosing CBG: How much CBG to take?

Like all things cannabis, figuring out a dosage that works for you is a personal journey that should be guided by a doctor, especially if you’re taking medications or have any health issues.

With that being said, we didn’t find any good sources for dosing CBG on the internet at the time of publishing this post, so it’s back to the olden days of cannabis guinea pigging.

All of the current sources we could find were trying to sell CBG products and we unfortunately couldn’t find any really solid data that we could pull from.

I personally have found that taking two 10mg doses of CBG per day works for me, and I balance that with 10mg of CBD and about 3-4mg of THC in each dose. That’s my personal happy place.

If you want to incorporate CBG into your world, the guidance is the same as other cannabinoids.

Start low. Go slow. Track, feel and document. Adjust as needed.

If you decide to use CBG, remember, every human body is different and we still know very little about this cannabinoid, especially when it comes to drug interactions. Never start taking anything or make changes to your health care routine without consulting a physician first, preferably one who has experience in cannabis.

Does CBG have side effects?

CBG has not shown notable side effects in rats and mice. Unfortunately, we don’t have sufficient data to say whether or not CBG causes a certain subset of side effects in Humans. 

But because CBG and CBD can interact with certain drugs, it can increase the side effects of other pharmaceuticals.

Where to buy CBG

With all of the “I don’t know”s and “talk to your doctor”s in this post aside, I love using CBG.

I like using as many cannabinoids as I can and CBG has helped me and my fellow guinea pigs feel better than using CBD or THC alone.

I smoke it, vape it or use it orally just about every day. I’ve also experimented with it as a topical.

If you’re an experimental critter like me, you’re probably like “STFU lady… and let me try it for myself.”

Like you, I’m pretty uptight about sourcing plant material.

Because I’ve personally seen so much crap sprayed on this medicine and have seen it grown in ways that are detrimental to the planet, I only use things that are:

  • organically grown using organic inputs
  • good for the ecosystem and grown on small family farms
  • affordable
  • and convenient (big bonus if it gets delivered to my door)

This is currently the only place I buy my CBD and CBG plant material for DIY infusions and tinctures because it meets all of those requirements.

If you’re looking for an affordable premade CBD:CBG oil so you don’t have to fuss with a recipe, I love this one.

Has CBG helped you?

While the research is still light, the recent availability of high CBG strains has created more anecdotal evidence.

Even though this isn’t scientific, we can learn so much from each others’ experiences and approaches to cannabis.

Please share your experience with CBG in the comments below so we can all keep learning.

And remember, this is a community effort. If you do find a good resource or research that can help us better understand CBG, please comment below or share it to [email protected]

with love,





Corinne Tobias

My name is Corinne Tobias and I’m the creator of this site that is all about cannabis and health (and having a good time combining those things!). Since 2013, I’ve helped millions of people on their cannabis journey and have been featured in publications like High Times, Merry Jane, Jezelbel, Westword, and Vice.

40 thoughts on “What is CBG and what is it good for? (with actual data and research)”

  1. This is very interesting. My mother has been asking me about this and I have not had any good answers for her. I will forward her the article and hope to find more research.

  2. CBG is custom made for ME, in my humble opinion. Brain, Cancer, chemo brain, etc.
    I’m in remission and want to stay there without any more poisonous, helpful medication.
    Than you, Thank you, Thank you!!

  3. I started making CBG infusions a few months ago. I love this cannabinoid. Alone…a nice mood booster. Combined with a low THC/high CBD cannabis…super without the “high”! Has helped a couple of friends with pain issues, too when taken under the tongue. (I personally, make a version of Bulletproof coffee with my oils…truly wake & bake. Or drizzle a bit over a pasta dish or salad.) Corinne, your website is really the best place to synthesize all the info that’s out there. A great starting place for research. And your recipes are helpful foundations for experimenting. Take care.

    1. Thank you for your kind feedback!
      Readers like you make it all possible!
      We are so happy you are finding success with cannabis and sharing with your friends!!
      You are awesome!

  4. Thank you so much Corinne for this post and especially for linking to Sacred Smoke. I’ve been using herbs and botanicals for a while in smoking blends, and sometimes will incorporate some into my cannabis blends. I am so grateful you are here for the world!

  5. I have been using CBG to combat arthritis. I made cannabutter (with Cocoa butter) – then used that to make a batch of chocolate drops. Each drop has 10mg of CBG (assuming my dosing is correct). After about a week, my OA infected joints felt looser – with the drop in inflammation, then pain started to subside. Just to test my theory, I stopped for a week – pain an inflammation came back. I’d like to hear back from any other CBG users if they have had similar results. I’m trying to talk my doctor into starting a clinical trial, but we would need a “medical grade” product to move forward.

  6. After I read that CBG was an antibacterial and had been successful in fighting MRSA, I thought I would infuse some with CBD and a little THC in olive oil to try on peri oral dermatitis that have been struggling with for months. After two months of antibiotics, I quit taking them and started applying the CBG/CBD/THC oil on my face and taking it sublingually. The rash has diminished! Fingers crossed it will continue working and could help other women with this infection.
    CBG/CBD/THC mix has also helped me avoid taking narcotic pain meds after breaking my hip last Thursday. Helps me relax and glide through the pain.

  7. I’m trying to follow you, honestly. Where is the beginning of all this? acidic precursors? #cbgresearch has a post on “Mother of Cannabinoids” that explains some of the basics, but where is the rest? Can you unpack this, and give me some pointers or hypertext links to relevant information?
    I Lost Alice to colon cancer, that might have been preventable (?). I have two friends…one had a stroke, the other suffers from Parkinson’s. Are these conditions treatable with CBG? One is a dentist, the other is a retired radiologist, neither is going to readily accept anecdotal evidence. Is there research to support?

    1. Hey Michael,
      Great questions! I’ll add these to our CBG FAQ!
      In the blog post we have some links to studies you can click on. Stay tuned because we have more CBG posts coming soon!

      -Maddie (Team Wake + Bake)

  8. I’ve been using cbd about a year. Does it take a while to feel the effects? Not sure I feel any differently. I get inflammation in my lungs. My grandfather had Alzheimer’s and I want to help prevent it. Can cbg help with this?

  9. Thank you for the CBG info. I’ve used your dosage calculator and it worked great! I will definitely use it again for making CBG oil ?

  10. Hi Mike,
    Great that it’s helping.
    Have you tried topicals? (That’s what I’m using now. Still in process of acquiring CBG material.).

  11. Since I added CBG to my CBD infusions my mood and energy levels seem improved. It has also reduced inflammation in my G I tract.

  12. I’ve been using CBG since I heard about it from you for arthritis pain. I picked up an ounce from the link and infused Cocoa Butter and then made chocolate If i did my calcs correctly, its ~200mg per chocolate bar – 10 mg per piece. Your recommendation of 20mg a day works very well, and after a couple days, my joints (arthritic joints) a much looser and the pain is gone. Thank you Corinne! you are the best!

  13. I can tell you this…I’ve been making cbd oils, edibles and salves for several years now. People have loved them all. However, about 9 months ago I began incorporating CBG into all three. The result is almost all of my customers have noticed a considerable upgrade in the affect and efficacy of the cbg products. CBG has now become my “go to” cannabinoid. It’s just what my customers want.

  14. I have just come across your article and it has me thinking. I did a report on Lyme disease in college and one of the big issues with the disease isn’t from the actual bacteria but the body’s immune response causing inflammation…especially in the brain.
    I’m wondering if CBG has been studied in relation to Lyme disease?

  15. Omg! After suffering knee pain forever, I talked my non cannabis user husband into trying some residual left from my infusing CBGa in coconut oil. He could not believe the relief he experienced. He continued taking a dose every single day for weeks. Meanwhile, he had a follow up eye doctor visit for a dangerously, borderline glaucoma test result from a few months earlier. The eye doctor could not explain his drop in, and now normal, numbers.
    It was not until I found a tiny article about CBG mentioning a positive link to CBG and Glaucoma, that caused me to make the connection. I’m not sure how this could be as studies need to be carried out of course.
    However, My husband, now a fan of cannabis, is thrilled; and takes his dose every, single day.

  16. The CBD strain I use for my autistic son’s tincture is called Stem Cell and it’s 10.550% CBG. I get the flower at Healthful Flowers in Tucson.

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